MHNR Network, LLC

The Rehab

MHNR Network, LLC

  • Gary Aston Jones: Treating Addiction With Dual Orexin Receptor Antagonists

Gary Aston Jones: Treating Addiction With Dual Orexin Receptor Antagonists

Friday 24th March 2023

Dr. Gary Aston-Jones discusses the role of orexin in addiction and how dual orexin receptor antagonists might reduce cravings and aid recovery.
Explicit
52 minutes
Informative
Empowering
Thought-provoking
Engaging
Transformative

About this podcast

The Rehab
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MHNR Network, LLC
Overview:
Categories:
Innovative Treatments & Recovery Paths
Recovery Reimagined
Nutritional Pathways to Recovery
Family Recovery from Addiction
Creative Recovery Journeys
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Unlocking Addiction Treatment with Dr. Gary Aston-Jones

But this seems like a good adjunct therapy to other kinds of therapy.
Ever wondered how sleep could be the key to overcoming addiction? Dr. Gary Aston-Jones, Director of the Rutgers Brain Health Institute, joins 'The Rehab' podcast to shed light on this intriguing connection. With a career dedicated to understanding the brain's mysteries, Dr. Aston-Jones dives into the role of orexin, a neuropeptide that regulates arousal, wakefulness, and appetite, and its link to addiction.
He introduces us to dual orexin receptor antagonists, a class of medications initially designed to promote sleep but now showing promise in reducing cravings and drug-seeking behaviors. Dr. Aston-Jones shares compelling research from his lab, revealing how these antagonists can target the orexin system to help individuals struggling with addiction. By blocking orexin receptors, these medications not only aid sleep but also decrease hypermotivation linked to drug-associated stimuli, potentially preventing relapse. Throughout the episode, Dr.
Aston-Jones emphasizes the need for personalized addiction treatment and discusses the cognitive effects of long-term stimulant use. He also explores the future of addiction therapy, highlighting the importance of enhancing executive function to improve self-control and awareness. This episode is a treasure trove of insights for anyone interested in the science behind addiction and innovative treatment approaches.
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