Brain Lesions and Addiction: Unveiling New Treatment Targets
The study found that lesions that disrupted smoking addiction occurred in many different brain locations but were characterized by a specific pattern of brain connectivity. These results were reproducible across independent lesion cohorts and were associated with reduced alcohol addiction risk.
Ever wondered how brain lesions might affect addiction? This episode of 'This Week in Addiction Medicine' dives into a fascinating study published in Nature Medicine that explores this very question. The research analyzed patients addicted to smoking who experienced focal brain damage, uncovering a specific pattern of brain connectivity linked to addiction remission. This discovery could pave the way for new therapeutic targets for neuromodulation, offering hope for those battling addiction. But that's just the beginning.
The episode also sheds light on a study examining racial and ethnic disparities in buprenorphine and extended-release naltrexone prescriptions during the COVID pandemic. Alarmingly, it found significant decreases in prescription fills for Black, Hispanic, and Asian patients, while white patients saw no such decline. Additionally, listeners will learn about hyperkatifeia, a condition marked by heightened negative emotional symptoms during withdrawal from alcohol and drugs.
The podcast also covers binge drinking among moderate drinkers, revealing its strong link to multiple alcohol problems both immediately and years later. For those interested in jail-based treatment for opioid use disorder, there's a qualitative study featuring interviews with staff at New Jersey county jails about their current practices. Lastly, the episode delves into the effectiveness of cannabis-based products for chronic pain.
While synthetic products with high THC to CBD ratios showed moderate pain relief, they also increased sedation and dizziness. Products with balanced THC to CBD ratios offered slight pain improvement but came with a higher risk of sedation and nausea. Whether you're a healthcare professional, someone affected by addiction, or just curious about the latest in addiction medicine, this episode is packed with valuable insights.