American Society of Addiction Medicine

This Week in Addiction Medicine from ASAM

American Society of Addiction Medicine

  • Lead: Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial

Lead: Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial

Tuesday 29th April 2025

Explore how varenicline helps youth quit vaping and dive into pressing issues in addiction medicine.
6 minutes
Informative
Educational
Eye-opening
Supportive
Engaging

About this podcast

This Week in Addiction Medicine from ASAM
Author:
American Society of Addiction Medicine
Overview:
Categories:
Innovative Treatments & Recovery Paths
Navigating Alcohol Dependency
Family Recovery from Addiction
Nutritional Pathways to Recovery
Navigating Intimate Relationships
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Youth Vaping: Can Varenicline Make a Difference?

Episode Overview

  • Varenicline shows promise in helping youth quit vaping.
  • Higher abstinence rates with varenicline compared to placebo.
  • Dual use of cigarettes and e-cigarettes poses health risks.
  • Prenatal opioid or cocaine use leads to adverse neonatal outcomes.
  • Digital health apps may compromise user privacy.
Continuous abstinence rates were higher in the varenicline group than in the placebo group - 51% vs 14%.
In this episode of 'This Week in Addiction Medicine', the spotlight is on a groundbreaking study published in the Journal of the American Medical Association. The research focuses on the use of varenicline for helping young people quit nicotine vaping. It's a 12-week clinical trial involving 261 youths aged 16 to 25 who are seeking treatment. With the addition of brief behavioural support, varenicline showed promising results in promoting vaping cessation, boasting higher abstinence rates compared to a placebo.
The trial not only highlights the potential of varenicline but also reassures that adverse effects are comparable to those experienced with a placebo. As the episode unfolds, it also touches on other intriguing studies in the addiction medicine field. You'll hear about the risks associated with dual use of combustible cigarettes and e-cigarettes, and the sobering outcomes for newborns when mothers consume opioids or cocaine during pregnancy.
The discussion extends to forced treatment discontinuation among drug users in Rhode Island, shedding light on the complexities of addiction treatment. A particularly eye-opening segment addresses the need for transparency in addiction research, especially with animal models of opioid addiction. The importance of transparency practices like open data and bias-reducing methods is underscored, aiming to improve research reproducibility.
Privacy concerns in digital health apps also come under scrutiny, with calls for more secure platforms to protect sensitive health information from being exploited. This episode offers a rich tapestry of information for anyone interested in addiction medicine, combining research findings with real-world implications. Whether you're keen on understanding youth vaping cessation or the broader challenges in addiction treatment, this episode has something to offer. Don't miss out on these valuable insights.
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