Recovery Discovery | Breaking the Cycle: How Genetic Testing and Behavior Can Prevent AddictionRecovery Discovery | Breaking the Cycle: How Genetic Testing and Behavior Can Prevent Addiction
Show Up and Stay | Sobriety to Sustainable Recovery
James Piacentino discusses how genetics and behaviour intersect in preventing addiction, sharing insights from his work with Thrive Genetics and personal experiences.
29:41•21 Jan 2026
Genetics and Behaviour: A New Approach to Addiction Prevention
Episode Overview
- Understanding genetic predisposition can help prevent addiction.
- Behavioural factors are as crucial as genetics in addiction risk.
- Intergenerational trauma plays a significant role in addiction.
- CARES aims to provide early warnings for potential substance use disorders.
- The healthcare industry can benefit from integrating genetic testing.
“"Addiction is not just one person's battle; it's a family affair."”
Curious about how science and genetics can play a role in addiction prevention? This episode of 'Show Up and Stay' is a must-listen for anyone interested in the intersection of technology and recovery. Hosts DeAnn and Craig Knighton engage in an enlightening conversation with James Piacentino, co-founder and CEO of Thrive Genetics. James shares his personal journey with intergenerational addiction and how it inspired him to create the Comprehensive Addiction Risk Evaluation System (CARES).
The discussion unravels the complexities of addiction risk, highlighting how genetics and behaviour contribute to the likelihood of developing a substance use disorder. James's story is both compelling and relatable, as he discusses the emotional trauma associated with addiction and the potential for genetic testing to prevent future struggles. The episode touches on the importance of understanding one's genetic predisposition to addiction, especially when facing medical treatments that could lead to dependency.
With a mix of science, personal anecdotes, and a dash of humour, this episode provides a fresh perspective on addiction prevention. It's an eye-opener for those who have ever wondered about the role of genetics in their own or their loved ones' recovery journeys. So, are you ready to rethink how we approach addiction risk? Tune in to find out how technology could change the future of recovery.

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