14. Early Life Trauma and Opioid Use Disorder14. Early Life Trauma and Opioid Use Disorder
Addiction Medicine Journal Club
Explore how early life trauma impacts opioid addiction with insights from Drs. Keenan and Del Tredici.
28:26•9 Jan 2023
Unpacking Early Life Trauma's Role in Opioid Addiction
“Patients with early life trauma are more vulnerable to opiate use disorder. Of course, I will be particularly careful about my opioid prescribing and counseling in this population.”
Have you ever wondered how childhood experiences shape adult behavior, especially when it comes to addiction? This episode of 'Addiction Medicine Journal Club' dives into the connection between early life trauma and opioid use disorder. Hosts Dr. John Keenan and Dr. Sonia Del Tredici discuss a revealing study that highlights how stress from early life trauma can increase the risk of developing opioid addiction later in life, independent of depression and anxiety.
The hosts share personal anecdotes from their practice, adding a relatable touch to the scientific findings. They also explore an opinion piece on AMA (Against Medical Advice) discharges, shedding light on how stigma in addiction medicine can worsen patient outcomes. Additionally, the episode covers the groundbreaking development of a new fentanyl vaccine aimed at reducing the drug's harmful effects.
With a blend of research, real-world insights, and practical advice, this episode offers a comprehensive look at how early experiences can shape addiction and what can be done to mitigate these risks.

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