242. Dr. John Hsu | iPill dispenser

242. Dr. John Hsu | iPill dispenser

High Truths on Drugs and Addiction

iPill - a devise to ensure medication compliance. Is this something that methadone clinic patients can use to ensure safety? Dr. John Hsu has practiced anesthesia, chronic pain management, addiction medicine for 31 years.  He is now on a quest to address the opioid epidemic. He has started three companies, including: IPill Dispenser - a medical device for remote medication adherence monitoring. It is a FDA breakthrough designated product and holds six patents for it. Quivive Pharma - drug development company that has combined opioids with a respiratory stimulant. He is running a clinical trial at the Cleveland clinic and a supported by a $1.9 million NIDA/NIH grant.  He holds three patents for this company. Fentavive - a drug development company that has combined Narcan with a respiratory stimulant to address dosing ambiguity with Narcan. He holds one patent for this company.

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50:3711 Aug 2025

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Ensuring Medication Compliance with iPill

Episode Overview

  • iPill ensures remote medication adherence.
  • Opioid and benzodiazepine combination poses high risk.
  • Face print technology enhances prescription security.
  • Fentanyl's potential as a weapon of mass destruction.
  • Importance of medication compliance to prevent deaths.
The app uses your face print to make sure only the prescription holder gets access to pills at only the prescribed dose and time.

In this enlightening episode of High Truths on Drugs and Addiction, Dr. Roneet Lev hosts Dr. John Hsu, an expert in anesthesia, chronic pain management, and addiction medicine. Dr. Hsu discusses his innovative work tackling the opioid epidemic, focusing on the iPill dispenser—a groundbreaking medical device designed to ensure medication compliance through remote monitoring.

This device uses face print technology to ensure that only the prescription holder can access their medication at the prescribed dose and time, thus aiming to reduce misuse and improve safety. Medication compliance is a critical issue, especially in the context of the opioid epidemic. Dr. Lev recalls her research during the peak of opioid prescriptions, noting that medication compliance could have prevented many deaths. Dr.

Hsu elaborates on the risks associated with opioid and benzodiazepine combinations, identifying them as a red flag due to their high potential for overdose. The conversation also touches on broader drug safety issues, including the alarming use of fentanyl as a weapon of mass destruction, illustrated by past incidents involving aerosolized carfentanyl. Dr. Hsu highlights the urgent need for effective interventions and technologies to combat these threats.

This episode underscores the importance of integrating public health and safety measures to address substance use impacts. Dr. Lev and Dr. Hsu advocate for innovative solutions, such as the iPill dispenser, to improve medication adherence and reduce the stigma surrounding opioid use disorder. Listeners are encouraged to engage with the content, support programs like Drug Free America Foundation, and visit hightruths.com for more insights.

The episode is a call to action for individuals and communities to implement strategies that save lives and foster a healthier society.

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