Kratom Vomit Sex Story PLUS Blake Mycoskie on Depression, Psychedelics & “I Am Enough” Dopey WednesdayKratom Vomit Sex Story PLUS Blake Mycoskie on Depression, Psychedelics & “I Am Enough” Dopey Wednesday
Dopey: On the Dark Comedy of Drug Addiction
Timestamp Notes 00:02 – Dopey Wednesday theme song 01:03 – Dave reacts to Reddit saying he sounds like a radio announcer 02:00 – Film festival update: SVA Theatre / old Walter Reade Triplex 02:38 – Dave remembers growing up in Penn South 03:30 – Penn South flea market memories 04:35 – Dave says this is “not very dopey” and introduces Blake Mycoskie 05:45 – Traumatic Aunt Elsa flea market story 07:22 – Ian from Paris voicemail begins 08:10 – Vodka, kratom, and friend-with-benefits setup 09:31 – Kratom vomit explosion in the bathroom 11:43 – Ian praises Dopey socks 12:30 – Dave reacts to the “sexy vomit time” kratom story 14:03 – Dave asks for international voicemails 14:30 – Dave apologizes for falsely saying Chet Holmgren is gay 15:45 – Spotify comments begin 16:28 – Leah corrects Dave on Salvia and Sassafras 17:40 – Euphoria and Zach Noe Towers comments 18:00 – Amanda de Cadenet backlash 18:51 – Katz’s food and chicken soup/brisket secret 20:00 – White Claw relapse comments 21:17 – Justin Bagby recovery comment 22:20 – More Chet Holmgren corrections 23:21 – Patreon comments begin 24:00 – Rachel shares 27 days off alcohol and 7 days off coke 24:45 – Sassafras debate continues 26:20 – Lena Dunham, Girls, Knicks, and Zach Noe Towers praise 28:00 – Dave introduces Blake Mycoskie 29:10 – Blake joins; No Magic Pill and Shark Tank 30:10 – Shark Tank during COVID at the Venetian 31:30 – Dave talks about being addicted to Shark Tank 32:25 – Blake discusses psychedelics and funding Johns Hopkins research 34:20 – Blake on dopamine addiction, startups, racing, climbing, surfing 36:00 – Blake’s depression after selling TOMS 37:30 – Origin of TOMS: Argentina, polo, and shoes 40:00 – One-for-one shoe idea is born 41:00 – Dave talks about discomfort with “helping people” 42:00 – Blake explains AI therapy app Sonia 45:30 – Why TOMS took off with hipsters, Brooklyn, Vogue, and celebrities 48:00 – Blake discusses selling TOMS and moving to Jackson Hole 50:00 – Depression, shame, and chasing fixes 51:45 – Blake lists treatments he tried for depression 52:50 – Psychedelic experiences: Ayahuasca, MDMA, psilocybin, San Pedro, Ibogaine 53:40 – Ibogaine made Blake nauseous but gave no psychedelic effect 56:45 – Blake talks about getting off Abilify, Lamictal, Wellbutrin, and Klonopin 58:30 – Misdiagnosed as bipolar at a dinner party 59:40 – Blake describes suicidal depression and feeling imprisoned by his life 01:01:15 – Blake realizes he can blow up his life instead of ending it 01:03:40 – Thank God for Depression book 01:05:15 – Alternative to Meds Center in Sedona 01:06:00 – Brain zaps and pharmaceutical withdrawal 01:08:20 – San Pedro journey and discovering “I am enough” 01:10:35 – 40-day mantra meditation practice 01:12:50 – Photography project helps Blake regain connection and creativity 01:15:30 – Portrait of sober friend at the Dream Center 01:17:30 – Dave and Blake discuss photography and portraits 01:19:00 – Morning Water 01:20:00 – Enough bracelets and giving one to someone else 01:22:00 – No Magic Pill guests: Matthew McConaughey, Michael Pollan, Jewel 01:24:00 – Blake pushes back on Dave saying he doesn’t do Dopey to help people 01:26:30 – Dave jokes about MDMA and heroin with Oprah 01:27:00 – Advice for people getting off pharmaceuticals 01:28:30 – Blake stops drinking with Jasmine 01:29:30 – Psychedelics, no weed, no alcohol, quitting nicotine 01:31:00 – “Have you ever met somebody who actually was not enough?” 01:32:00 – Dave agrees to the 40-day “I am enough” challenge 01:32:35 – Dave wraps up Blake interview 01:33:00 – Dave jokes about “Great” t-shirts and Dopey vs. Phish
1:37:21•13 May 2026
Kratom Chaos and “I Am Enough”: Dark Humour Meets Mental Health with Blake Mycoskie
Episode Overview
- Mixing substances like vodka and kratom can lead to extreme and dangerous physical reactions, even for people without a history of opiate use.
- Selling a business or hitting a life milestone doesn’t guarantee happiness; major success can actually trigger depression and loss of purpose.
- Coming off psychiatric medications such as Abilify, Lamictal, Wellbutrin and Klonopin needs to be done very slowly with an experienced psychiatrist to reduce serious withdrawal risks.
- Psychedelic-assisted work (for Blake, a guided San Pedro session) can help uncover core beliefs such as “I’m not enough”, but it is a starting point, not a quick cure.
- Daily practices like a repeated “I am enough, I’ve always been enough” mantra and creative projects can gradually rebuild self-worth and support recovery from both depression and addictive patterns.
“I think that I've never felt that I was enough.”
Curious about how others navigate their sobriety journey? This episode of Dopey throws together classic "drugs, addiction, and dumb shit" chaos with an unusually reflective chat on mental health, depression, and meaning. Things kick off with Dave riffing on Reddit criticism, childhood memories of New York flea markets, and a hilariously graphic voicemail from Ian in Paris about mixing vodka, kratom, sex, and a catastrophic bathroom "fire hose of vomit".
It’s grim, it’s messy, and it’s exactly the sort of dark comedy regular Dopey fans expect. From there, the tone shifts as entrepreneur Blake Mycoskie joins. Best known for founding TOMS shoes and giving away “100 million fucking pairs of shoes”, Blake openly says he’s not a drug addict or alcoholic, but he has wrestled with depression and a relentless need for dopamine.
He talks about selling TOMS, moving to Jackson Hole to snowboard, and then crashing into a deep depressive period where he was misdiagnosed as bipolar and put on multiple psychiatric medications. Blake explains how coming off Abilify, Lamictal, Wellbutrin and Klonopin nearly broke him, leading him to an alternative-to-meds centre, careful tapering, and a guided San Pedro (mescaline) experience.
In that session he realised, “I think that I've never felt that I was enough,” which sparked a long slog of healing, including a 40‑day mantra practice repeating “I am enough, I've always been enough.” He now channels his energy into mental health projects like his “I Am Enough” bracelet (sold in pairs so you can give one away) and his podcast No Magic Pill, insisting there’s no quick fix, just slow, deliberate work.
Dave keeps things irreverent, poking fun at himself while clearly relating to the idea of chasing dopamine. If you're in recovery, questioning meds, or just tired of feeling “not enough”, this mix of filthy humour and honest struggle might be exactly what you need today. How would your life change if you actually believed you were enough?

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