Lead: Rapid vs Standard Induction to Injectable Extended-Release BuprenorphineLead: Rapid vs Standard Induction to Injectable Extended-Release Buprenorphine
This Week in Addiction Medicine from ASAM
The episode explores a clinical trial comparing rapid and standard induction to injectable buprenorphine, highlighting its effectiveness and retention rates.
7:08•11 Nov 2025
Rapid vs Standard Induction: A Deep Dive into Buprenorphine Trials
Episode Overview
- Rapid induction shows higher retention rates than standard induction.
- Adolescent cannabis use linked to later mental and physical health issues.
- Parental remission offers limited protective effects on offspring.
- Stigma around medications for AUD is low, yet knowledge is limited.
- GLP-1 receptor agonists show promise in treating substance use disorders.
“"RI was well-tolerated and had higher retention than SI at extended-release buprenorphine injection 2 overall and in fentanyl-positive participants."”
Get ready to dive into the nitty-gritty of addiction medicine with 'This Week in Addiction Medicine from ASAM.' This episode focuses on a pivotal study comparing rapid induction (RI) versus standard induction (SI) to injectable extended-release buprenorphine. With 729 participants, the trial examines the effectiveness and safety of RI in individuals using opioids or fentanyl. The results show RI not only being well-tolerated but also having higher retention rates than SI, especially among fentanyl-positive participants.
The episode doesn't stop there; it also touches on intriguing studies about adolescent cannabis use, parental remission effects on offspring, and stigma around medications for alcohol use disorder. The host, Zach Caruso, guides listeners through the latest findings, making complex medical jargon accessible and engaging. If you're curious about how the medical community is tackling addiction or want to learn more about treatment options, this episode is a must-listen.
So, are you ready to explore these groundbreaking studies and their implications for addiction medicine?
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