Microdosing 101: Gentle Medicine, Big Results

Microdosing 101: Gentle Medicine, Big Results

The Gris Alves‘s Podcast Tales of Recovery

Host Gris Alves and guest Adrian Lozano talk about microdosing psilocybin and mescaline, sharing personal experiences, protocols and safety considerations. They discuss how intention, community and gentle plant medicine practices may support recovery, mental health and everyday life changes.

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42:4921 May 2026

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Microdosing 101: Gentle Plant Medicine for Big Life Changes

Episode Overview

  • Microdosing offers a gentle, sub‑perceptual way to work with psilocybin and mescaline that can be integrated into daily life instead of relying on frequent big ceremonies.
  • Intention, ritual, journalling and practices like yoga, breathwork and meditation are key to turning microdosing from “just a pill” into a meaningful healing practice.
  • Protocols such as Fadiman’s, Stamets’ and five‑days‑on/two‑days‑off can be useful starting points, but people are encouraged to listen to their bodies and adapt intuitively.
  • Some clients, under medical supervision, have used microdosing alongside therapy and community support to gradually taper off SSRIs, reduce anxiety and shift coping patterns, including alcohol use.
  • Community, practitioner guidance and integration circles help people feel less alone, process emotions safely and build new patterns that support long‑term wellbeing.
With microdosing, we have micro shifts, macro impact.

Curious about how others manage their sobriety journey with the help of plant medicine? This conversation on Tales of Recovery brings together host Gris Alves and guest Adrian Lozano for a down‑to‑earth chat on microdosing psilocybin, mescaline (San Pedro/huachuma), and other sacred plants. Across the episode, they break down what a microdose actually is, how it differs from a full “ceremony” dose, and why many people prefer this “gentle, subtle way to work with the medicine” in everyday life.

Adrian shares how big ayahuasca ceremonies initially left him “in the deep end”, and how microdosing later became a bridge into safer, more sustainable healing. Gris talks about slipping small mushroom doses into honey, journalling, gardening, and suddenly realising she was “writing songs and in a good mood.” They get specific about protocols like the Fadiman and Stamets methods, stacking with lion’s mane or San Pedro, and why there’s no one‑size‑fits‑all approach.

The focus is on intention, ritual, and listening to your body: “There’s a difference between taking a microdose and having an intentional microdose practice.” For anyone in recovery or wrestling with anxiety, depression, or long‑term medication, their stories hit close to home. They describe clients gradually tapering off SSRIs (with medical support), people drinking less, sleeping better, and feeling more resilient, all while stressing that psychiatric meds can still be life‑saving for some.

There’s also plenty on community: integration circles, practitioner support, and the microdosing community around Mycology Psychology. As Adrian puts it, “With microdosing, we have micro shifts, macro impact.” If you’ve ever wondered whether gentle doses of plant medicine could support sobriety, nervous system health, or just a kinder inner dialogue, this chat might give you some useful food for thought. What small shift could you be ready for next?

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