Overdose risk, opioid agonists and other medications with Eleni DomzaridouOverdose risk, opioid agonists and other medications with Eleni Domzaridou
Addiction Audio
A cohort study using linked care and mortality records
18:21•17 Aug 2023
Balancing Act: Medications and Overdose Risks in Opioid Use Disorder
Episode Overview
- Dr. Eleni Domzaridou discusses the complexities of prescribing opioid agonists concurrently with other medications and their association with non-fatal overdose risk.
- The study addresses the critical need for evidence from real-world data in the current literature, highlighting challenges and practicalities of using electronic health records for comprehensive analysis.
- Dr. Domzaridou emphasizes the importance of educating patients about the unpredictable results of combining different drugs and the potential implications for policymakers and healthcare professionals.
- The episode offers valuable insights for clinicians, researchers, and policymakers, shedding light on the complexities and potential risks associated with prescribing medications for individuals with opioid use disorder.
- The discussion delves into the implications of the study's findings, emphasizing the need for a more personalised model of care for patients with opioid use disorder.
“I would emphasize that patients need education. So they need to understand that combining different drugs may have unpredictable results.”
When it comes to managing opioid use disorder, the balancing act of prescribing medications can be tricky. In this episode of 'Addiction Audio', Dr. Rob Calder chats with Dr. Eleni Domzaridou about her eye-opening research on the risks of non-fatal overdoses among those prescribed opioid agonists alongside other medications like benzodiazepines, gabapentinoids, and antipsychotics. Dr. Domzaridou explains why keeping an eye on non-fatal overdoses is crucial for preventing fatal ones.
She also dives into the nitty-gritty of using large datasets from GP surgeries to uncover patterns and associations between different prescribed drugs and overdose risks. This episode is a must-listen for anyone keen on understanding the real-world complexities of medication management in opioid use disorder.
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