S2 Ep20: #31 Medications for Alcohol Use Disorder 2.0 with Dr Stephen HoltS2 Ep20: #31 Medications for Alcohol Use Disorder 2.0 with Dr Stephen Holt
The Curbsiders Addiction Medicine Podcast
Dr Stephen Holt discusses advanced medication options for treating alcohol use disorder, focusing on patient-centred care and building trust.
1:01:49•24 Mar 2025
Advanced Medication Options for Alcohol Use Disorder with Dr Stephen Holt
Episode Overview
- Explore advanced medication options beyond naltrexone and acamprosate.
- Understand the importance of aligning treatment with patient goals.
- Learn about the benefits and challenges of using disulfiram.
- Gain insights into building trust and showing compassion in addiction medicine.
- Discover practical advice for healthcare professionals treating AUD.
“"Treating patients as human beings and showing compassion can build trust and make a significant impact."”
In this episode of The Curbsiders Addiction Medicine Podcast, Dr Stephen Holt from Yale University School of Medicine joins the hosts to discuss advanced medication options for treating alcohol use disorder (AUD). Dr Holt, an award-winning educator and addiction medicine specialist, shares his expertise on medications beyond the first line of treatment. This episode goes in-depth into alternatives like disulfiram, topiramate, and other options when standard treatments like naltrexone and acamprosate are not suitable.
Dr Holt's approach focuses on aligning treatment with patient goals, whether that's complete abstinence or reducing alcohol consumption. His passion for treating patients with compassion and building trust shines through as he explains the importance of a patient-centred approach in addiction medicine. The conversation is peppered with anecdotes and practical advice, making it both informative and engaging.
If you're a healthcare professional or someone interested in the complexities of AUD treatment, this episode is packed with valuable insights that can help you better understand the available medication options and how to work effectively with patients. Tune in to learn how to elevate your practice and support those battling alcohol use disorder.

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