Episode 39 - Hyperalgesia (Part I) “Big Foot”: Mechanisms and DiagnosisEpisode 39 - Hyperalgesia (Part I) “Big Foot”: Mechanisms and Diagnosis
The Addiction Connection
Drs. Bell and DeVine explore whether opioid-induced hyperalgesia is real, breaking down its mechanisms and diagnosis.
20:31•15 Dec 2020
Is Opioid-Induced Hyperalgesia Real? Drs. Bell and DeVine Investigate
“We like to believe the opposite of addiction is actually connection and we are going to attempt to educate you and possibly even entertain you while we navigate all topics.”
Can opioids, which are supposed to relieve pain, actually make it worse? Drs. Heather Bell and Kurt DeVine dive into this puzzling topic in Episode 39 of 'The Addiction Connection'. They tackle the concept of opioid-induced hyperalgesia, often dubbed the 'Big Foot' of opioid issues due to its elusive nature. Is it a myth or a real phenomenon?
The doctors break down the science behind it, explaining how long-term opioid use might lead to increased sensitivity to pain instead of relief. They also differentiate between hyperalgesia and allodynia, two terms that are often confused but are crucial to understanding this condition. Drs. Bell and DeVine discuss the inflammatory processes and tolerance levels that play a role in long-term opioid use and its paradoxical effects.
They emphasize the importance of ruling out other causes of pain to accurately diagnose hyperalgesia. This episode is not just for medical professionals but for anyone curious about the complexities of addiction and pain management. With their usual blend of humor and expertise, Drs. Bell and DeVine make a complicated subject accessible and engaging. Tune in for a fascinating look at one of the most controversial topics in opioid treatment.

Do you want to link to this podcast?
Get the buttons here!
More From This Show
The latest episodes from the same podcast.
Related Episodes
Similar episodes from other shows in the catalogue.
